Repurposing Penfluridol in Combination with Temozolomide for the Treatment of Glioblastoma

Repurposing Penfluridol in Combination with Temozolomide for the Treatment of Glioblastoma

Despite the presence of aggressive treatment strategies, glioblastoma remains intractable, warranting a novel therapeutic modality. An oral antipsychotic agent, penflurido (PFD), used for schizophrenia treatment, has shown an antitumor effect on various types of cancer cells. As glioma sphere-formin...

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Bibliographic Details
Main Authors: Hyungsin Kim, Kyuha Chong, Byung-Kyu Ryu, Kyung-Jae Park, Mi OK Yu, Jihye Lee, Seok Chung, Seongkyun Choi, Myung-Jin Park, Yong-Gu Chung, Shin-Hyuk Kang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
penfluridol
sphere forming cell
tumor growth
temozolomide
glioblastoma
Online Access:https://www.mdpi.com/2072-6694/11/9/1310

Internet

https://www.mdpi.com/2072-6694/11/9/1310

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