PTPN22 1858C>T polymorphism distribution in Europe and association with rheumatoid arthritis: case-control study and meta-analysis.

OBJECTIVE: The PTPN22 rs2476601 polymorphism is associated with rheumatoid arthritis (RA); nonetheless, the association is weaker or absent in some southern European populations. The aim of the study was to evaluate the association between the PTPN22 rs2476601 polymorphism and RA in Italian subjects...

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Main Authors: Michele Ciro Totaro, Barbara Tolusso, Valerio Napolioni, Francesca Faustini, Silvia Canestri, Alice Mannocci, Elisa Gremese, Silvia Laura Bosello, Stefano Alivernini, Gianfranco Ferraccioli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3174938?pdf=render