Brain and Retinal Abnormalities in the 5xFAD Mouse Model of Alzheimer's Disease at Early Stages

Brain and Retinal Abnormalities in the 5xFAD Mouse Model of Alzheimer's Disease at Early Stages

One of the major challenges in treating Alzheimer's disease (AD) is its early diagnosis. Increasing data from clinical and animal research indicate that the retina may facilitate an early diagnosis of AD. However, a previous study on the 5xFAD (a fast AD model), showing retinal changes before t...

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Bibliographic Details
Main Authors: Mengrong Zhang, Liting Zhong, Xiu Han, Guoyin Xiong, Di Xu, Sensen Zhang, Haiyang Cheng, Kin Chiu, Ying Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer's disease
retinal ganglion cell
multielectrode array
long-term potentiation
photoreceptor
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.681831/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.681831/full

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