Metabolic and kidney disorders correlate with high atazanavir concentrations in HIV-infected patients: is it time to revise atazanavir dosages?

Metabolic and kidney disorders correlate with high atazanavir concentrations in HIV-infected patients: is it time to revise atazanavir dosages?

INTRODUCTION:Ritonavir-boosted atazanavir (ATV/r) is a relatively well tolerated antiretroviral drug. However, side effects including hyperbilirubinemia, dyslipidemia, nephrolithiasis and cholelithiasis have been reported in the medium and long term. Unboosted ATV may be selected for some patients b...

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Bibliographic Details
Main Authors: Cristina Gervasoni, Paola Meraviglia, Davide Minisci, Laurenzia Ferraris, Agostino Riva, Simona Landonio, Valeria Cozzi, Nitin Charbe, Lara Molinari, Giuliano Rizzardini, Emilio Clementi, Massimo Galli, Dario Cattaneo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4398451?pdf=render

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http://europepmc.org/articles/PMC4398451?pdf=render

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