Ferulic acid inhibits LPS-induced apoptosis in bovine mammary epithelial cells by regulating the NF-κB and Nrf2 signalling pathways to restore mitochondrial dynamics and ROS generation

Abstract In bovine mammary epithelial cells (BMECs), a cascade of inflammatory reactions induced by lipopolysaccharide (LPS) has been shown to result in cell injury and apoptosis. The present study aims to reveal the protective effect of ferulic acid (FA) on LPS-induced BMEC apoptosis and explore it...

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Bibliographic Details
Main Authors: Mingjiang Liu, Chi Zhang, Xiaolong Xu, Xin Zhao, Ziyi Han, Dandan Liu, Ruonan Bo, Jingui Li, Zongping Liu
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Veterinary Research
Subjects:
LPS
FA
Online Access:https://doi.org/10.1186/s13567-021-00973-3