SarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates of Staphylococcus aureus LAC and UAMS-1

SarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates of Staphylococcus aureus LAC and UAMS-1

Using DNA affinity chromatography we demonstrate that the S. aureus regulatory proteins MgrA, Rot, SarA, and SarS bind DNA baits derived from the promoter regions associated with the genes encoding aureolysin, ScpAB, SspABC, and SplA-F. Three of four baits also bound SarR and SarZ, the exception in...

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Bibliographic Details
Main Authors: Aura M. Ramirez, Karen E. Beenken, Stephanie D. Byrum, Alan J. Tackett, Lindsey N. Shaw, Brittney D. Gimza, Mark S. Smeltzer
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Virulence
Subjects:
staphylococcus aureus
extracellular protease
regulation
biofilm
sara
rot
mgra
sars
sarz
sarr
Online Access:http://dx.doi.org/10.1080/21505594.2020.1855923

Internet

http://dx.doi.org/10.1080/21505594.2020.1855923

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