Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors

Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors

Abstract Background Rett syndrome (RTT) is a progressive neurodevelopmental disease that is characterized by abnormalities in cognitive, social, and motor skills. RTT is often caused by mutations in the X-linked gene encoding methyl-CpG binding protein 2 (MeCP2). The mechanism by which impaired MeCP...

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Bibliographic Details
Main Authors: Suzy Varderidou-Minasian, Lisa Hinz, Dominique Hagemans, Danielle Posthuma, Maarten Altelaar, Vivi M. Heine
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Molecular Autism
Subjects:
Rett syndrome
iPSC
Neuron differentiation
Quantitative mass spectrometry
TMT-10plex
Online Access:http://link.springer.com/article/10.1186/s13229-020-00344-3

Internet

http://link.springer.com/article/10.1186/s13229-020-00344-3

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