Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors
Abstract Background Rett syndrome (RTT) is a progressive neurodevelopmental disease that is characterized by abnormalities in cognitive, social, and motor skills. RTT is often caused by mutations in the X-linked gene encoding methyl-CpG binding protein 2 (MeCP2). The mechanism by which impaired MeCP...
Main Authors: | Suzy Varderidou-Minasian, Lisa Hinz, Dominique Hagemans, Danielle Posthuma, Maarten Altelaar, Vivi M. Heine |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | Molecular Autism |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13229-020-00344-3 |
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