Andrographolide Attenuates LPS-Induced Cardiac Malfunctions Through Inhibition of IκB Phosphorylation and Apoptosis in Mice

Andrographolide Attenuates LPS-Induced Cardiac Malfunctions Through Inhibition of IκB Phosphorylation and Apoptosis in Mice

Background/Aims: Cardiac malfunction is a common complication in sepsis and significantly increases the mortality of patients in septic shock. However, no studies have examined whether andrographolide (And) reduces LPS-induced myocardial malfunction. Methods: Left ventricular systolic and diastolic...

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Bibliographic Details
Main Authors: Jinlong Zhang, Didi Zhu, Yulin Wang, Yunfeng Ju
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Cardiac malfunction
LPS
Apoptosis
Andrographolide
Online Access:http://www.karger.com/Article/FullText/438528

Internet

http://www.karger.com/Article/FullText/438528

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