The Escape of Temperature-Sensitive T Antigen Immortalized Rat Hepatocytes from Conditional Immortalization

Conditionally immortalized hepatocytes (CIH) established with a gene for the temperature-sensitive mutant of the T antigen (tsT) have characteristics to stop proliferating and to differentiate at nonpermissive temperatures (37—39°C) due to inactivation of the T antigen. Therefore, they may be a good...

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Main Authors: Byung-Ho Kim M.D., Yo Seb Han, Bong-Keun Choe, Hyeseong Cho, Gi Deog Nam, Jin Woo Lee, Young Il Kim, Jai Kyung Park, Seok Ho Dong, Hyo Jong Kim, Young Woon Chang, Joung Il Lee, Rin Chang
Format: Article
Language:English
Published: SAGE Publishing 2005-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000005783982864