Role of Hydroxamate-Based Histone Deacetylase Inhibitors (Hb-HDACIs) in the Treatment of Solid Malignancies

Hydroxamate-based histone deacetylase inhibitors (Hb-HDACIs), such as vorinostat, belinostat and panobinostat, have been previously shown to have a wide range of activity in hematologic malignancies such as cutaneous T-cell lymphoma and multiple myeloma. Recent data show that they synergize with a v...

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Bibliographic Details
Main Authors: Marinella Zilli, Laura Iezzi, Felice Simiele, Antonino Grassadonia, Pasquale Cioffi, Clara Natoli
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/5/3/919