Rsk2 Knockdown in PC12 Cells Results in Sp1 Dependent Increased Expression of the Gria2 Gene, Encoding the AMPA Receptor Subunit GluR2

The RSK2 protein is a member of the RSK serine-threonine protein kinase family and is encoded by the X-linked rps6ka3 gene in human. Highly heterogeneous loss-of-function mutations affecting this gene are responsible for a severe syndromic form of cognitive impairment, Coffin-Lowry syndrome. RSK2, w...

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Bibliographic Details
Main Authors: André Hanauer, Solange Pannetier, Anne Schneider, Tahir Mehmood
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:International Journal of Molecular Sciences
Subjects:
Sp1
Online Access:http://www.mdpi.com/1422-0067/14/2/3358