Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure

Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure

Abstract Background The high-density lipoprotein receptor SR-B1 mediates cellular uptake of several lipid species, including cholesterol and vitamin E. During early mouse development, SR-B1 is located in the maternal-fetal interface, where it facilitates vitamin E transport towards the embryo. Conse...

Full description

Bibliographic Details
Main Authors: Nicolás Santander, Carlos Lizama, Leandro Murgas, Sebastián Contreras, Alberto J. M. Martin, Paz Molina, Alonso Quiroz, Katherine Rivera, Francisca Salas-Pérez, Alejandro Godoy, Attilio Rigotti, Dolores Busso
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Genomics
Subjects:
SR-B1
Neural tube defects
RNA-Seq
Androgen receptor
Gene expression
Online Access:http://link.springer.com/article/10.1186/s12864-018-5110-2

Internet

http://link.springer.com/article/10.1186/s12864-018-5110-2

Similar Items