Pertactin contributes to shedding and transmission of Bordetella bronchiseptica.

Whooping cough is resurging in the United States despite high vaccine coverage. The rapid rise of Bordetella pertussis isolates lacking pertactin (PRN), a key vaccine antigen, has led to concerns about vaccine-driven evolution. Previous studies showed that pertactin can mediate binding to mammalian...

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Bibliographic Details
Main Authors: Longhuan Ma, Kalyan K Dewan, Dawn L Taylor-Mulneix, Shannon M Wagner, Bodo Linz, Israel Rivera, Yang Su, Amanda D Caulfield, Uriel Blas-Machado, Eric T Harvill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009735