Selenium, selenoenzymes, oxidative stress and risk of neoplastic progression from Barrett's esophagus: results from biomarkers and genetic variants.

Clinical trials have suggested a protective effect of selenium supplementation on the risk of esophageal cancer, which may be mediated through the antioxidant activity of selenoenzymes. We investigated whether serum selenium concentrations, selenoenzyme activity, oxidative stress and genetic variati...

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Bibliographic Details
Main Authors: Yumie Takata, Alan R Kristal, Regina M Santella, Irena B King, David J Duggan, Johanna W Lampe, Margaret P Rayman, Patricia L Blount, Brian J Reid, Thomas L Vaughan, Ulrike Peters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3371043?pdf=render