MART-10, a New Generation of Vitamin D Analog, Is More Potent than 1α,25-Dihydroxyvitamin D3 in Inhibiting Cell Proliferation and Inducing Apoptosis in ER+ MCF-7 Breast Cancer Cells

MART-10, a New Generation of Vitamin D Analog, Is More Potent than 1α,25-Dihydroxyvitamin D3 in Inhibiting Cell Proliferation and Inducing Apoptosis in ER+ MCF-7 Breast Cancer Cells

Hormone antagonist therapy for estrogen receptor positive (ER+) breast cancer patients post radical surgery and radiation therapy has a poor prognosis and also causes bone loss. 1α,25-dihydroxyvitamin D3 [1α,25(OH)2D3] is a potent antitumor agent in pre-clinical studies, but caused hypercalcemia whe...

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Bibliographic Details
Main Authors: Kun-Chun Chiang, Chun-Nan Yeh, Shin-Cheh Chen, Shih-Che Shen, Jun-Te Hsu, Ta-sen Yeh, Jong-Hwei S. Pang, Li-Jen Su, Masashi Takano, Atsushi Kittaka, Horng-Heng Juang, Tai C. Chen
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2012/310872

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http://dx.doi.org/10.1155/2012/310872

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