The effect of metabolic stress on genome stability of a synthetic biology chassis Escherichia coli K12 strain

Abstract Background Synthetic organism-based biotechnologies are increasingly being proposed for environmental applications, such as in situ sensing. Typically, the novel function of these organisms is delivered by compiling genetic fragments in the genome of a chassis organism. To behave predictabl...

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Bibliographic Details
Main Authors: Jillian M. Couto, Anne McGarrity, Julie Russell, William T. Sloan
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-018-0858-2