Development and optimization of orthotopic liver metastasis xenograft mouse models in uveal melanoma

Development and optimization of orthotopic liver metastasis xenograft mouse models in uveal melanoma

Abstract Background Patients with metastatic uveal melanoma (MUM) in the liver usually die within 1 year. The development of new treatments for MUM has been limited by the lack of diverse MUM cell lines and appropriate animal models. We previously reported that orthotopic xenograft mouse models esta...

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Bibliographic Details
Main Authors: Takahito Sugase, Bao Q. Lam, Meggie Danielson, Mizue Terai, Andrew E. Aplin, J. Silvio Gutkind, Takami Sato
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Translational Medicine
Subjects:
Uveal melanoma
Orthotopic xenograft model
Liver metastasis
Spleen
Liver
Online Access:http://link.springer.com/article/10.1186/s12967-020-02377-x

Internet

http://link.springer.com/article/10.1186/s12967-020-02377-x

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