Addressing confounding artifacts in reconstruction of gene co-expression networks
Abstract Gene co-expression networks capture biological relationships between genes and are important tools in predicting gene function and understanding disease mechanisms. We show that technical and biological artifacts in gene expression data confound commonly used network reconstruction algorith...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-05-01
|
| Series: | Genome Biology |
| Online Access: | http://link.springer.com/article/10.1186/s13059-019-1700-9 |