The <it>BRCA1 </it>Ashkenazi founder mutations occur on common haplotypes and are not highly correlated with anonymous single nucleotide polymorphisms likely to be used in genome-wide case-control association studies

The <it>BRCA1 </it>Ashkenazi founder mutations occur on common haplotypes and are not highly correlated with anonymous single nucleotide polymorphisms likely to be used in genome-wide case-control association studies

<p>Abstract</p> <p>Background</p> <p>We studied linkage disequilibrium (LD) patterns at the <it>BRCA1 </it>locus, a susceptibility gene for breast and ovarian cancer, using a dense set of 114 single nucleotide polymorphisms in 5 population groups. We focused...

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Bibliographic Details
Main Authors: Zhang Jinghui, Ellis Nathan A, Offit Kenneth, Greene Mark H, Fonseca Libia R, Rowe William H, Pineda Marbin A, Pereira Lutécia, Collins Andrew, Struewing Jeffery P
Format: Article
Language:English
Published: BMC 2007-10-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/8/68

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http://www.biomedcentral.com/1471-2156/8/68

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