Cell-Cycle Kinases Coordinate the Resolution of Recombination Intermediates with Chromosome Segregation

Homologous recombination leads to the formation of DNA joint molecules (JMs) that must be resolved to allow chromosome segregation, but how resolution is temporally coupled with chromosome segregation is unknown. Here, we have analyzed the role of the cell-cycle kinases Cdk and Cdc5 in coordinating...

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Bibliographic Details
Main Authors: Joao Matos, Miguel G. Blanco, Stephen C. West
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713002726