A computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data.

Given the association of disturbances in non-esterified fatty acid (NEFA) metabolism with the development of Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease, computational models of glucose-insulin dynamics have been extended to account for the interplay with NEFA. In this study, we use arteri...

Full description

Bibliographic Details
Main Authors: Shauna D O'Donovan, Michael Lenz, Roel G Vink, Nadia J T Roumans, Theo M C M de Kok, Edwin C M Mariman, Ralf L M Peeters, Natal A W van Riel, Marleen A van Baak, Ilja C W Arts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007400