Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions

Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions

Abstract Uncharacterized and unannotated open-reading frames, which we refer to as novel open reading frames (nORFs), may sometimes encode peptides that remain unexplored for novel therapeutic opportunities. To our knowledge, no systematic identification and characterization of transcripts encoding...

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Bibliographic Details
Main Authors: Chaitanya Erady, Adam Boxall, Shraddha Puntambekar, N. Suhas Jagannathan, Ruchi Chauhan, David Chong, Narendra Meena, Apurv Kulkarni, Bhagyashri Kasabe, Kethaki Prathivadi Bhayankaram, Yagnesh Umrania, Adam Andreani, Jean Nel, Matthew T. Wayland, Cristina Pina, Kathryn S. Lilley, Sudhakaran Prabakaran
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-020-00167-4

Internet

https://doi.org/10.1038/s41525-020-00167-4

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