Circulating Cell Biomarkers in Pulmonary Arterial Hypertension: Relationship with Clinical Heterogeneity and Therapeutic Response

Circulating Cell Biomarkers in Pulmonary Arterial Hypertension: Relationship with Clinical Heterogeneity and Therapeutic Response

Background: Endothelial dysfunction is central to PAH. In this study, we simultaneously analysed circulating levels of endothelial microvesicles (EMVs) and progenitor cells (PCs) in PAH and in controls, as biomarkers of pulmonary endothelial integrity and evaluated differences among PAH subtypes and...

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Bibliographic Details
Main Authors: Olga Tura-Ceide, Isabel Blanco, Jéssica Garcia-Lucio, Roberto del Pozo, Agustín Roberto García, Elisabet Ferrer, Isabel Crespo, Diego A. Rodríguez-Chiaradia, Carmen Pilar Simeon-Aznar, Manuel López-Meseguer, Clara Martín-Ontiyuelo, Víctor I. Peinado, Joan Albert Barberà
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
pulmonary arterial hypertension
endothelial dysfunction
biomarkers
progenitor cells
endothelial extracellular vesicles
PAH-specific treatment
Online Access:https://www.mdpi.com/2073-4409/10/7/1688

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https://www.mdpi.com/2073-4409/10/7/1688

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