Phase I trial of carboplatin and gemcitabine chemotherapy and stereotactic ablative radiosurgery for the palliative treatment of persistent or recurrent gynecologic cancer

Phase I trial of carboplatin and gemcitabine chemotherapy and stereotactic ablative radiosurgery for the palliative treatment of persistent or recurrent gynecologic cancer

Background: We conducted a phase I trial to determine the safety of systemic chemotherapy prior to abdominopelvic robotic stereotactic ablative radiotherapy (SABR) in women with persistent or recurrent gynecologic cancers. Methods: Patients were assigned to dose-finding cohorts of day-1 carboplatin...

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Bibliographic Details
Main Authors: Charles A Kunos, Tracy M Sherertz, Mazen eMislmani, Rodney J Ellis, Simon S Lo, Steven E Waggoner, Kristine M Zanotti, Karin eHerrmann, Robert L Debernardo
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Oncology
Subjects:
Carboplatin
Radiation
Stereotactic radiosurgery
ovarian cancer
endometrial cancer
gemcitabine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00126/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00126/full

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