Delphinidin-3-O-glucoside inhibits angiogenesis via VEGFR2 downregulation and migration through actin disruption

Delphinidin-3-O-glucoside inhibits angiogenesis via VEGFR2 downregulation and migration through actin disruption

Excessive angiogenesis favours cancer development, allowing cancer invasion. Polyphenols are promising chemopreventive agents, although data gather so far in respect of anthocyanins, namely cyanidin-3-O-glucoside and delphinidin-3-O-glucoside (DG) and respective aglycones are scarce. The capability...

Full description

Bibliographic Details
Main Authors: Olga Viegas, Miguel A. Faria, Joana B. Sousa, Martin Vojtek, Salomé Gonçalves-Monteiro, Joanna Suliburska, Carmen Diniz, Isabel M.P.L.V.O. Ferreira
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Journal of Functional Foods
Subjects:
Anthocyanins
Anti-proliferative
Anti-invasive
MDA-MB-231 cells
CAM assay
Breast cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464619300398

Internet

http://www.sciencedirect.com/science/article/pii/S1756464619300398

Similar Items