Silencing BRE expression in human umbilical cord perivascular (HUCPV) progenitor cells accelerates osteogenic and chondrogenic differentiation.

BRE is a multifunctional adapter protein involved in DNA repair, cell survival and stress response. To date, most studies of this protein have been focused in the tumor model. The role of BRE in stem cell biology has never been investigated. Therefore, we have used HUCPV progenitor cells to elucidat...

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Bibliographic Details
Main Authors: Elve Chen, Mei Kuen Tang, Yao Yao, Winifred Wing Yiu Yau, Lok Man Lo, Xuesong Yang, Yiu Loon Chui, John Chan, Kenneth Ka Ho Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720665?pdf=render