The Crumbs_C isoform of Drosophila shows tissue- and stage-specific expression and prevents light-dependent retinal degeneration

The Crumbs_C isoform of Drosophila shows tissue- and stage-specific expression and prevents light-dependent retinal degeneration

Drosophila Crumbs (Crb) is a key regulator of epithelial polarity and fulfils a plethora of other functions, such as growth regulation, morphogenesis of photoreceptor cells and prevention of retinal degeneration. This raises the question how a single gene regulates such diverse functions, which in m...

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Bibliographic Details
Main Authors: Stephanie Spannl, Alexandra Kumichel, Sarita Hebbar, Katja Kapp, Marcos Gonzalez-Gaitan, Sylke Winkler, Rosana Blawid, Gregor Jessberger, Elisabeth Knust
Format: Article
Language:English
Published: The Company of Biologists 2017-02-01
Series:Biology Open
Subjects:
Epithelial polarity
EGF-like repeat
Alternative splicing
Mutually exclusive exon
Online Access:http://bio.biologists.org/content/6/2/165

Internet

http://bio.biologists.org/content/6/2/165

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