Whole exome sequencing reveals a biallelic frameshift mutation in GRXCR2 in hearing impairment in Cameroon

Abstract Background Hearing impairment (HI) genes are poorly studied in African populations. Methods We used whole exome sequencing (WES) to investigate pathogenic and likely pathogenic (PLP) variants in 10 individuals with HI, from four multiplex families from Cameroon, two of which were previously...

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Bibliographic Details
Main Authors: Ambroise Wonkam, Kamogelo Lebeko, Shaheen Mowla, Jean Jacques Noubiap, Mike Chong, Guillaume Pare
Format: Article
Published: Wiley 2021-03-01
Series:Molecular Genetics & Genomic Medicine
Online Access:https://doi.org/10.1002/mgg3.1609