Whole exome sequencing reveals a biallelic frameshift mutation in GRXCR2 in hearing impairment in Cameroon
Abstract Background Hearing impairment (HI) genes are poorly studied in African populations. Methods We used whole exome sequencing (WES) to investigate pathogenic and likely pathogenic (PLP) variants in 10 individuals with HI, from four multiplex families from Cameroon, two of which were previously...
Main Authors: | Ambroise Wonkam, Kamogelo Lebeko, Shaheen Mowla, Jean Jacques Noubiap, Mike Chong, Guillaume Pare |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-03-01
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Series: | Molecular Genetics & Genomic Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/mgg3.1609 |
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