Crosstalk between Activated and Inactivated c-Src in Hepatocellular Carcinoma

C-Src activity is regulated by tyrosine phosphorylation at two distinct sites, Tyr416 and Tyr527, with opposite effects. However, the clinical roles of these sites in human cancers are not well defined. This study aims to determine whether the alterations and crosstalk of these two sites may contrib...

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Bibliographic Details
Main Authors: Mei-Lin Chen, Chee-Yin Chai, Kun-Tu Yeh, Shen-Nien Wang, Chia-Jung Tsai, Yao-Tsung Yeh, Sheau-Fang Yang
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2011-0792