Altered ribosomal function and protein synthesis caused by tau

Altered ribosomal function and protein synthesis caused by tau

Abstract The synthesis of new proteins is a fundamental aspect of cellular life and is required for many neurological processes, including the formation, updating and extinction of long-term memories. Protein synthesis is impaired in neurodegenerative diseases including tauopathies, in which patholo...

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Bibliographic Details
Main Authors: Harrison Tudor Evans, Deonne Taylor, Andrew Kneynsberg, Liviu-Gabriel Bodea, Jürgen Götz
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Acta Neuropathologica Communications
Subjects:
FTD
Neurodegeneration
Polysome profiling
Protein synthesis
Ribosomes
Tau
Online Access:https://doi.org/10.1186/s40478-021-01208-4

Internet

https://doi.org/10.1186/s40478-021-01208-4

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