Biology before the SOS Response—DNA Damage Mechanisms at Chromosome Fragile Sites

The <i>Escherichia coli</i> SOS response to DNA damage, discovered and conceptualized by Evelyn Witkin and Miroslav Radman, is the prototypic DNA-damage stress response that upregulates proteins of DNA protection and repair, a radical idea when formulated in the late 1960s and early 1970...

Full description

Bibliographic Details
Main Authors: Devon M. Fitzgerald, Susan M. Rosenberg
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/9/2275