Injury to the Spinal Cord Niche Alters the Engraftment Dynamics of Human Neural Stem Cells

The microenvironment is a critical mediator of stem cell survival, proliferation, migration, and differentiation. The majority of preclinical studies involving transplantation of neural stem cells (NSCs) into the CNS have focused on injured or degenerating microenvironments, leaving a dearth of info...

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Bibliographic Details
Main Authors: Christopher J. Sontag, Nobuko Uchida, Brian J. Cummings, Aileen J. Anderson
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114000848