Differential prognostic impact of platelet-derived growth factor receptor expression in NSCLC

Differential prognostic impact of platelet-derived growth factor receptor expression in NSCLC

Abstract Preclinical evidence suggests that stromal expression of platelet-derived growth factor receptors (PDGFRs) stimulates tumor development and diminishes intratumoral drug uptake. In non-small cell lung cancer (NSCLC), the clinical relevance of stromal PDGFR expression remains uncertain. Tumor...

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Bibliographic Details
Main Authors: Thomas Karsten Kilvaer, Mehrdad Rakaee, Turid Hellevik, Jørg Vik, Luigi De Petris, Tom Donnem, Carina Strell, Arne Ostman, Lill-Tove Rasmussen Busund, Inigo Martinez-Zubiaurre
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-46510-3

Internet

https://doi.org/10.1038/s41598-019-46510-3

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