Jejunal proteins secreted by db/db mice or insulin-resistant humans impair the insulin signaling and determine insulin resistance.

Two recent studies demonstrated that bariatric surgery induced remission of type 2 diabetes very soon after surgery and far too early to be attributed to weight loss. In this study, we sought to explore the mechanism/s of this phenomenon by testing the effects of proteins from the duodenum-jejunum c...

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Bibliographic Details
Main Authors: Serenella Salinari, Cyrille Debard, Alessandro Bertuzzi, Christine Durand, Paul Zimmet, Hubert Vidal, Geltrude Mingrone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3577828?pdf=render