Dual Role of CD4 in Peripheral T Lymphocytes

The interaction of T-cell receptors (TCRs) with self- and non-self-peptides in the major histocompatibility complex (MHC) stimulates crucial signaling events, which in turn can activate T lymphocytes. A variety of accessory molecules further modulate T-cell signaling. Of these, the CD4 and CD8 corec...

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Bibliographic Details
Main Authors: Daniela Glatzová, Marek Cebecauer
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
CD4
Lck
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00618/full