Gene length and detection bias in single cell RNA sequencing protocols [version 1; referees: 2 approved]

Background: Single cell RNA sequencing (scRNA-seq) has rapidly gained popularity for profiling transcriptomes of hundreds to thousands of single cells. This technology has led to the discovery of novel cell types and revealed insights into the development of complex tissues. However, many technical...

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Bibliographic Details
Main Authors: Belinda Phipson, Luke Zappia, Alicia Oshlack
Format: Article
Language:English
Published: F1000 Research Ltd 2017-04-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-595/v1