Retromer in Synaptic Function and Pathology
The retromer complex mediates export of select transmembrane proteins from endosomes to the trans-Golgi network (TGN) or to the plasma membrane. Dysfunction of retromer has been linked with slowly progressing neurodegenerative disorders, including Alzheimer’s and Parkinson’s disease (AD and PD). As...
Main Authors: | Lennart Brodin, Oleg Shupliakov |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-10-01
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Series: | Frontiers in Synaptic Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fnsyn.2018.00037/full |
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