Regulation Is in the Air: The Relationship between Hypoxia and Epigenetics in Cancer

Regulation Is in the Air: The Relationship between Hypoxia and Epigenetics in Cancer

Hypoxia is an inherent condition of tumors and contributes to cancer development and progression. Hypoxia-inducible factors (HIFs) are the major transcription factors involved in response to low O<sub>2</sub> levels, orchestrating the expression of hundreds of genes involved in cancer ha...

Full description

Bibliographic Details
Main Authors: Diego Camuzi, Ísis Salviano Soares de Amorim, Luis Felipe Ribeiro Pinto, Leonardo Oliveira Trivilin, André Luiz Mencalha, Sheila Coelho Soares Lima
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
hypoxia
hypoxia-inducible factors
epigenetics
DNA methylation
histones modifications
cancer hallmarks
Online Access:https://www.mdpi.com/2073-4409/8/4/300

Internet

https://www.mdpi.com/2073-4409/8/4/300

Similar Items