Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells.

Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells.

The cell intrinsic programming that regulates mammalian primordial germ cell (PGC) development in the pre-gonadal stage is challenging to investigate. To overcome this we created a transgene-free method for generating PGCs in vitro (iPGCs) from mouse embryonic stem cells (ESCs). Using labeling for S...

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Bibliographic Details
Main Authors: John J Vincent, Ziwei Li, Serena A Lee, Xian Liu, Marisabel O Etter, Silvia V Diaz-Perez, Sara K Taylor, Sofia Gkountela, Anne G Lindgren, Amander T Clark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3240638?pdf=render

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http://europepmc.org/articles/PMC3240638?pdf=render

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