Prognostic Significance of the Pluripotency Factors NANOG, SOX2, and OCT4 in Head and Neck Squamous Cell Carcinomas

Prognostic Significance of the Pluripotency Factors NANOG, SOX2, and OCT4 in Head and Neck Squamous Cell Carcinomas

Cancer stem cells (CSCs) play major roles in tumor initiation, progression, and resistance to cancer therapy. Several CSC markers have been studied in head and neck squamous cell carcinomas (HNSCC), including the pluripotency factors NANOG, SOX2, and OCT4; however, their clinical significance is sti...

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Bibliographic Details
Main Authors: Daniel Pedregal-Mallo, Francisco Hermida-Prado, Rocío Granda-Díaz, Irene Montoro-Jiménez, Eva Allonca, Esperanza Pozo-Agundo, Mónica Álvarez-Fernández, César Álvarez-Marcos, Juana M. García-Pedrero, Juan Pablo Rodrigo
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
head and neck squamous cell carcinoma
NANOG
SOX2
OCT4
prognosis
lymph node metastasis
Online Access:https://www.mdpi.com/2072-6694/12/7/1794

Internet

https://www.mdpi.com/2072-6694/12/7/1794

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