Free Extracellular miRNA Functionally Targets Cells by Transfecting Exosomes from Their Companion Cells.

Lymph node and spleen cells of mice doubly immunized by epicutaneous and intravenous hapten application produce a suppressive component that inhibits the action of the effector T cells that mediate contact sensitivity reactions. We recently re-investigated this phenomenon in an immunological system....

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Bibliographic Details
Main Authors: Krzysztof Bryniarski, Wlodzimierz Ptak, Emilia Martin, Katarzyna Nazimek, Marian Szczepanik, Marek Sanak, Philip W Askenase
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4414541?pdf=render