Molecular Pathobiology of the Cerebrovasculature in Aging and in Alzheimers Disease Cases With Cerebral Amyloid Angiopathy

Molecular Pathobiology of the Cerebrovasculature in Aging and in Alzheimers Disease Cases With Cerebral Amyloid Angiopathy

Cerebrovascular dysfunction and cerebral amyloid angiopathy (CAA) are hallmark features of Alzheimer's disease (AD). Molecular damage to cerebrovessels in AD may result in alterations in vascular clearance mechanisms leading to amyloid deposition around blood vessels and diminished neurovascula...

Full description

Bibliographic Details
Main Authors: Joseph O. Ojo, Jon M. Reed, Gogce Crynen, Prashanthi Vallabhaneni, James Evans, Benjamin Shackleton, Maximillian Eisenbaum, Charis Ringland, Anastasia Edsell, Michael Mullan, Fiona Crawford, Corbin Bachmeier
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
cerebrovasculature
Alzheimers disease
cerebral amyloid angiopathy
endothelial cells
mural cells
proteomics
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.658605/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.658605/full

Similar Items