Characterization and risk association of polymorphisms in Aurora kinases A, B and C with genetic susceptibility to gastric cancer development

Characterization and risk association of polymorphisms in Aurora kinases A, B and C with genetic susceptibility to gastric cancer development

Abstract Background Single nucleotide polymorphisms (SNPs) in genes encoding mitotic kinases could influence development and progression of gastric cancer (GC). Methods Case-control study of nine SNPs in mitotic genes was conducted using qPCR. The study included 116 GC patients and 203 controls. In...

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Bibliographic Details
Main Authors: Aner Mesic, Marija Rogar, Petra Hudler, Nurija Bilalovic, Izet Eminovic, Radovan Komel
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Cancer
Subjects:
Gastric cancer
Single nucleotide polymorphisms
Mitotic kinases
Cancer susceptibility
Chromosomal instability
Online Access:http://link.springer.com/article/10.1186/s12885-019-6133-z

Internet

http://link.springer.com/article/10.1186/s12885-019-6133-z

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