Low-rank regularization for learning gene expression programs.

Learning gene expression programs directly from a set of observations is challenging due to the complexity of gene regulation, high noise of experimental measurements, and insufficient number of experimental measurements. Imposing additional constraints with strong and biologically motivated regular...

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Bibliographic Details
Main Authors: Guibo Ye, Mengfan Tang, Jian-Feng Cai, Qing Nie, Xiaohui Xie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3866120?pdf=render