Down-Regulation of Ribosomal S6 kinase RPS6KA6 in Acute Myeloid Leukemia Patients
Objective Signaling pathways such as extracellular regulated kinase/mitogen activated protein kinase (ERK/MAPK) have increased activity in leukemia. Ribosomal 6 kinase (RSK4) is a factor downstream of the MAPK/ERK pathway and an important tumor suppressor which inhibits ERK trafficking. Decrease...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Royan Institute (ACECR), Tehran
2016-07-01
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Series: | Cell Journal |
Subjects: | |
Online Access: | http://celljournal.org/web/journal/article/3672/download |