A gene-protein assay for human epidermal growth factor receptor 2 (HER2): brightfield tricolor visualization of HER2 protein, the <it>HER2</it> gene, and chromosome 17 centromere (CEN17) in formalin-fixed, paraffin-embedded breast cancer tissue sections

A gene-protein assay for human epidermal growth factor receptor 2 (HER2): brightfield tricolor visualization of HER2 protein, the <it>HER2</it> gene, and chromosome 17 centromere (CEN17) in formalin-fixed, paraffin-embedded breast cancer tissue sections

<p>Abstract</p> <p>Background</p> <p>The eligibility of breast cancer patients for human epidermal growth factor receptor 2 (HER2)-directed therapies is determined by the <it>HER2</it> gene amplification and/or HER2 protein overexpression status of the breas...

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Bibliographic Details
Main Authors: Nitta Hiroaki, Kelly Brian D, Padilla Mary, Wick Nikolaus, Brunhoeber Patrick, Bai Isaac, Singh Shalini, Ranger-Moore Jim, Bieniarz Chris, Tsuda Hitoshi, Grogan Thomas M
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Diagnostic Pathology
Subjects:
Gene-protein assay
Dual color <it>in situ</it> hybridization
Immunohistochemistry
HER2
Breast cancer
Online Access:http://www.diagnosticpathology.org/content/7/1/60

Internet

http://www.diagnosticpathology.org/content/7/1/60

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