Identification of a Human SOCS1 Polymorphism That Predicts Rheumatoid Arthritis Severity

Identification of a Human SOCS1 Polymorphism That Predicts Rheumatoid Arthritis Severity

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by an autoimmune response in the joints and an exacerbation of cytokine responses. A minority of patients with RA experience spontaneous remission, but most will show moderate/high disease activity, with aggressive joint damag...

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Bibliographic Details
Main Authors: Amalia Lamana, Ricardo Villares, Iria V. Seoane, Nuria Andrés, Pilar Lucas, Paul Emery, Edward M. Vital, Ana Triguero-Martínez, Ana Marquez, Ana M. Ortiz, Robin Maxime, Carmen Martínez, Javier Martín, Rosa P. Gomariz, Frederique Ponchel, Isidoro González-Álvaro, Mario Mellado
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
disease activity
cytokines
inflammation
biomarkers
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01336/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01336/full

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