Unique responses of stem cell-derived vascular endothelial and mesenchymal cells to high levels of glucose.

Diabetes leads to complications in selected organ systems, and vascular endothelial cell (EC) dysfunction and loss is the key initiating and perpetuating step in the development of these complications. Experimental and clinical studies have shown that hyperglycemia leads to EC dysfunction in diabete...

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Bibliographic Details
Main Authors: Emily Keats, Zia A Khan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3368917?pdf=render